NEUROLOGIC ASPECTS OF DIZZINESS

 

Definitions

Vertigo

Inner Ear Nystagmus

   Benign Positional Vertigo

      Dix-Hallpike maneuver

      Epley maneuver

   Meniere’s Syndrome

   Recurrent Vestibulopathy

Brain Stem (Ataxic Nystagmus)

   Brain Stem TIA or Stroke

   Cerebellar Hemorrhage

   Multiple Sclerosis

Presyncope

References

About This Document

 

Definitions:

   Dizziness is a generic term as used by patients for a feeling of unsteadiness or disorientation.  In some cases the cause may be emotional, manipulative or psychiatric.  In others a metabolic change may mimic symptoms as in hyperventilation.  This outline concerns the neurologic causes of dizziness. Vertigo is an illusion that self or the environment is moving, and indicates inner ear or brain disease.  Presyncope implies a feeling of faintness or sensory disturbance caused by a transient or progressive decrease in cerebral blood flow.  There is no hallucination of movement associated with presyncope.  Multisensory deficit produces unsteadiness in diabetics and elderly.  Psychogenic causes may mimic vertigo.  Romberg testing can help differentiate a cause.

 

Vertigo

   The cochlea and semicircular canals send messages about movement to the vestibular nucleus in the brain stem.  The brain stem sends this message to the temporal lobe where it reaches consciousness.  Vertigo  from inner ear malfunction is rarely dangerous.  Vertigo from brain stem disease is rarely benign.  Information from vision, vestibular system, nuchal musculature and proprioception is integrated in the cerebellum to produce equilibrium.

 

 

1.     Inner Ear Nystagmus:  The inner ear sends a false message of falling to the brain.  The eyes drift slowly towards the direction of the fall (primary phase).  The intact cerebral cortex responds by moving the eyes back quickly, resulting in repetitive jerky movements.  Inner ear nystagmus is horizontal or rotatory - never vertical.  This nystagmus can be suppressed by visual fixation and is fatigueable.  It is a result of brain stem deviation and cortical correction.  It cannot occur in coma.

·       Benign Positional Vertigo

The patient activates fluid in the posterior semicircular canal by moving the head back.  Vertigo lasts only a few seconds, has a latency of a few seconds, and tends to fatigue with repetition.  It tends to be self-limiting, but can persist or recur. Diagnosis and determination of the affected side is done using the Dix-Hallpike maneuver.

Once the affected side is determined, the Epley maneuver is used  to attempt repositioning of the offending otolith crystals to a less sensitive part of the inner ear.

·       Meniere’s Syndrome

Caused by accumulation of endolymph distending semicircular canals.  This is continuous with the inner ear.

Attacks of hearing loss, tinnitis and vertigo can last hours to days and tend to recur.

·       Recurrent Vestibulopathy

These are isolated attacks of vertigo only lasting several days.  Previously presumed to be viral, but the cause is not known.

 

2.   Brain Stem Vertigo:  Almost always associated with other neurologic symptoms from the brain stem (double vision, weakness, paresthesiae, incoordination).  Ataxic nystagmus is displayed.  Nystagmus beats in direction of gaze.  It can be vertical.  Eyes do not move in tandem.  Nystagmus is enhanced by visual fixation.  Nystagmus without vertigo is always CNS.  In intranuclear ophthalmoplegia only one eye moves when the patient looks to one side

·       Posterior Circulation TIA or Stroke

Posterior circulation fills with clot.  Occurs in older patients with recurrent dizzy spells.  Risk factors for stroke exist, or patient may have known atherosclerosis, heart disease, neck bruits or arrhythmia predisposing to vascular pathology.  Other brain stem symptoms usually associated.  Difference in arm BP can imply subclavian stenosis leading to this mechanism.  CT or MRI shows evidence of current or past stroke.

·       Cerebellar Hemorrhage

Uncommon condition presenting in patients with severe untreated hypertension.  Sudden violent vertigo, vomiting, posterior headache, diplopia, ataxia, decreasing level of consciousness, deviation of eyes, slurred speech.  CT or MRI in acute stage may show hemorrhage but not infarct.  Refer to a neurosurgeon.

·       Multiple Sclerosis

Younger patient with brain stem vertigo.  Vertigo rare in first attack.  Multiple lesions in vestibular nucleus on MRI.  If this is inconclusive, triple evoked potentials may show evidence of asymptomatic lesions.

 

Presyncope

This is caused by transient decrease in global cerebral blood flow.  There is dizziness but not vertigo.  Compensatory adrenergic symptoms (tachycardia, hypertension, sweating, vasoconstriction, pallor).  Usually benign and vasovagal.  Can progress to syncope.  Can imply serious disease such as coronary disease,  hypovolemia, aortic stenosis or arrhythmia.

 

References

1.  Audio Digest Family Practice April 28, 2002.  Demystifying Dizziness.  Dr John Edmeads.

2.  http://www.vertigone.com/hallpike.htm

3.  http://www.tchain.com/otoneurology/disorders/bppv/epley/fifth.html

4.  Audio Digest Family Practice December 5, 1988.  Dizziness/Preoperative Examination.  Dr. Gregory L. Henry

 

prepared by N.J. Bosomworth, MD, CCFP

not peer reviewed

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Dix-Hallpike Maneuver

1.     The patient is seated with the head in neutral position

2.     The head is rotated 45 degrees to one side.

3.     The patient is briskly taken to the supine position with the head rotated.  Vertigo is reproduced if this is the affected side.

4.     The patient is returned to the sitting head-neutral position.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Epley Maneuver

1.     The patient is seated with the head in neutral position.

2.     The head is rotated 45 degrees to the affected side determined by the Dix-Hallpike maneuver.

3.     The patient is briskly taken to the supine position with the head rotated.  Remain in this position 30-60 sec.  Vertigo will result.

4.     The head is rotated 45 degrees to the other side and held 30-60 seconds.  Vertigo will result.

5.     The patient is rolled 45 degrees to the same side as (4) with the neck rotated the same 45 degrees.  The face will be directed to the floor.  This is held 30 seconds.  Vertigo will result.

6.     The patient is returned to the sitting position with the head inclined forward for 1 minute.

7.     The maneuver  can be repeated 2 or 3 times if tolerated.

8.     If this is successful, recurrence is about 30%.  

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Romberg Testing

1.        In end organ disease, patient falls toward the lesion and the environment tends to move away from the involved side.

2.        If results poor with eyes open, generally a cerebellar problem

3.        If results good with eyes open and poor with eyes closed, suspect a proprioceptive problem.